![]() ![]() ![]() The genetic disorder McCune-Albright syndrome can also present Cushing's syndrome in affected patients. Steroid-producing adrenal tumours and hyperplasias of the zona fasciculata result in excess cortisol production and are the cause for adrenal Cushing's syndrome. Analysis of correlation revealed that the morphologically identifiable ZR thickness corresponded well to the thickness of the ZR that was immunopositive for HSD17B5 in both male (A, r0.99, p<0.01) and female adrenals (B, r0.99, p<0. In certain animals such as rodents, the lack of 17alpha-hydroxylase results in the synthesis of corticosterone instead of cortisol. ZG, zona glomerulosa ZF, zona fasciculata ZR, zona reticularis M, medulla. This tissue also generates a small amount of weak androgens. The zona fasciculata chiefly produces glucocorticoids (mainly cortisol in the human), which regulates the metabolism of glucose, especially in times of stress (e.g. It is the thickest of the three adrenal layers, measuring approximately 0.9mm and making up 50 of the mass of the Adrenal Gland. Constituent cells are organized into bundles or 'fascicles'. The Zona Fasciculata is the middle zone of the Adrenal Cortex, deep to the Zona Glomerulosa and superficial to the Zona Reticularis. These regulate the water and electrolyte. The zona fasciculata (sometimes, fascicular or fasciculate zone) constitutes the middle and also the widest zone of the adrenal cortex, sitting directly. The zona fasciculata constitutes the middle zone of the adrenal cortex, sitting directly beneath the zona glomerulosa. Aldosterone: These are the steroid hormones which are released from the zona glomerulosa layer of the adrenal cortex. zona fasciculata of suprarenal gland (exact synonym, ).adrenal gland zona fasciculata (exact synonym, ). ![]()
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